Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646373 | 0.93 | L3MBTL1 (0.54) | ALDH1A1L3MBTL1KDM4EGLAGAA | |
| SCHEMBL9526882 | 0.86 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1KDM4EGLAGAA | |
| SCHEMBL7647544 | 0.84 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1KDM4EGLAGAA | |
| SCHEMBL9525981 | 0.84 | KDM4E (0.48) | ALDH1A1L3MBTL1KDM4EGLAGAA | |
| SCHEMBL9702887 | 0.84 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1KDM4EGLAGAA | |
| SCHEMBL7646385 | 0.82 | PDE5A (0.44) | ALDH1A1L3MBTL1KDM4EGLAGAA | |
| SCHEMBL7646452 | 0.80 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1KDM4EGLAGAA | |
| SCHEMBL27154849 | 0.78 | PIM1 (0.62) | ALDH1A1L3MBTL1KDM4EGLAGAA | |
| SCHEMBL9702581 | 0.77 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1KDM4EGLAGAA | |
| SCHEMBL9526401 | 0.77 | PTPN1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |