Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521560 | 0.78 | MAPT (0.54) | MAPTL3MBTL1ALDH1A1HTR6MAPK1 | |
| SCHEMBL9521928 | 0.75 | ALDH1A1 (0.43) | MAPTL3MBTL1ALDH1A1HTR1ADRD2 | |
| SCHEMBL9522305 | 0.72 | MAPT (0.46) | MAPTALDH1A1HTR6HTR1ADRD2 | |
| SCHEMBL31220765 | 0.70 | MAPT (0.55) | MAPTL3MBTL1ALDH1A1MAPK1KDM4E | |
| SCHEMBL27565044 | 0.70 | DRD2 (0.46) | MAPTALDH1A1HTR6DRD2HTR2C | |
| SCHEMBL12714783 | 0.69 | ALDH1A1 (0.54) | MAPTL3MBTL1ALDH1A1HTR1ADRD2 | |
| SCHEMBL12491827 | 0.69 | POLB (0.53) | MAPTL3MBTL1ALDH1A1HTR6HTR1A | |
| SCHEMBL29789731 | 0.68 | ALDH1A1 (0.57) | MAPTL3MBTL1ALDH1A1HTR6MAPK1 | |
| SCHEMBL20605208 | 0.68 | ALDH1A1 (0.57) | MAPTL3MBTL1ALDH1A1HTR6MAPK1 | |
| SCHEMBL13958141 | 0.68 | MAPT (0.52) | MAPTL3MBTL1ALDH1A1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249043-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5086049-A | Bactericides | NIPPONSHINYAKU CO., LTD. (JP) | 1992-02-04 | — | — | US | disclosed |
| US-4843070-A | BACTERIDCIDES, FUNGICIDES | NIPPON SHINYAKU CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |