Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526385 | 0.81 | LMNA (0.40) | RAB9AKMT2ALMNAHSP90AA1MAPT | |
| SCHEMBL9526019 | 0.81 | RAB9A (0.56) | RAB9AKMT2AMEN1LMNAMAPT | |
| SCHEMBL10429975 | 0.81 | TDP1 (0.48) | RAB9AKMT2AMEN1LMNAHSP90AA1 | |
| SCHEMBL9527627 | 0.80 | RAB9A (0.50) | RAB9AKMT2AMEN1LMNACYP19A1 | |
| SCHEMBL9525716 | 0.78 | ITGA4 (0.54) | RAB9AKMT2AMEN1LMNACYP19A1 | |
| SCHEMBL27803980 | 0.75 | KMT2A (0.50) | RAB9AKMT2ALMNAHSP90AA1MAPT | |
| SCHEMBL9524051 | 0.72 | CYP19A1 (0.55) | RAB9AKMT2AMEN1LMNACYP19A1 | |
| SCHEMBL9523995 | 0.71 | RAB9A (0.58) | RAB9AKMT2AMEN1LMNAMAPT | |
| SCHEMBL20691188 | 0.70 | KMT2A (0.74) | RAB9AKMT2AMEN1LMNAMAPT | |
| SCHEMBL11842301 | 0.69 | KMT2A (0.51) | RAB9AKMT2AMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366542-B1 | 5-SUBSTITUTED ORTHO-AMINOPHENOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE OXIDATION DYEING OF KERATINIC FIBRES | L'OREAL (FR) | 1993-07-14 | — | — | EP | disclosed |
| EP-0366542-A1 | 5-Substituted ortho-aminophenols, process for their preparation and their use in the oxidation dyeing of keratinic fibres | L'OREAL (FR) | 1990-05-02 | — | — | EP | disclosed |