SCHEMBL9526215

SCHEMBL9526215

OC[C@H]1Oc2c(F)ccc(F)c2O[C@@H]1CO

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 2/20 0.31
LMNA P02545 2/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
GBA1 P04062 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9482152 0.80 CA2 (0.38)
SCHEMBL9481539 0.80 CA2 (0.38)
SCHEMBL9527323 0.76 SLC5A2 (0.31) SLC5A2LMNAGBA1
SCHEMBL9526535 0.71 AKR1B1 (0.32) SLC5A2LMNAGBA1
SCHEMBL9482188 0.69 PRKAB2 (0.39)
SCHEMBL9819549 0.69 PRKAB2 (0.39)
SCHEMBL7621430 0.69 RXFP1 (0.41)
SCHEMBL9525389 0.67 MAP3K14 (0.35) SLC5A2
SCHEMBL10980338 0.65 CA2 (0.36)
SCHEMBL10977242 0.65 CA2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0359290-B1 AROMATIC DIOLS GLAXO GROUP LIMITED (GB) 1993-08-04 EP claimed
EP-0359290-A1 Aromatic diols GLAXO GROUP LIMITED (GB) 1990-03-21 EP claimed
EP-0359290-B1 AROMATIC DIOLS GLAXO GROUP LIMITED (GB) 1993-08-04 EP disclosed
EP-0359290-A1 Aromatic diols GLAXO GROUP LIMITED (GB) 1990-03-21 EP disclosed