Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.35 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27257375 | 0.79 | RORC (0.39) | RORC | |
| SCHEMBL10441957 | 0.62 | TNF (0.30) | TNF | |
| SCHEMBL13233367 | 0.61 | CA12 (0.33) | — | |
| SCHEMBL28534882 | 0.61 | — | — | |
| SCHEMBL7885626 | 0.61 | IDH1 (0.42) | RPS6KA5RPS6KA4 | |
| SCHEMBL31138183 | 0.60 | MAPK10 (0.33) | RORC | |
| SCHEMBL7592088 | 0.60 | RPS6KA5 (0.48) | RPS6KA5RPS6KA4PANK3 | |
| SCHEMBL758549 | 0.59 | TP53 (0.37) | PTGS2 | |
| SCHEMBL7593026 | 0.59 | ALDH1A1 (0.60) | RPS6KA5RPS6KA4 | |
| SCHEMBL31205795 | 0.59 | NPSR1 (0.45) | RPS6KA5RPS6KA4PANK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338465-B1 | 1-CHLOROPYRIMIDINYL-1H-1,2,4-TRIAZOLE-3-SULFONAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS AGENTS WITH HERBICIDAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-06-02 | — | — | EP | claimed |
| US-4959094-A | HERBICIDES EFFECTIVE AGAINST MATRICARIA | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-09-25 | — | — | US | claimed |
| EP-0338465-A1 | 1-Chloropyrimidinyl-1H-1,2,4-triazole-3-sulfonamides, process for their preparation and their use as agents with herbicidal activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-10-25 | — | — | EP | claimed |
| JP-2042076-A | — | — | None | — | — | JP | disclosed |
| JP-2042076-A | — | — | None | — | — | JP | disclosed |
| EP-0338465-B1 | 1-CHLOROPYRIMIDINYL-1H-1,2,4-TRIAZOLE-3-SULFONAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS AGENTS WITH HERBICIDAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-06-02 | — | — | EP | disclosed |
| EP-0338465-B1 | 1-CHLOROPYRIMIDINYL-1H-1,2,4-TRIAZOLE-3-SULFONAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS AGENTS WITH HERBICIDAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-06-02 | — | — | EP | disclosed |
| US-4959094-A | HERBICIDES EFFECTIVE AGAINST MATRICARIA | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-09-25 | — | — | US | disclosed |
| US-4959094-A | HERBICIDES EFFECTIVE AGAINST MATRICARIA | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-09-25 | — | — | US | disclosed |
| US-4959094-A | HERBICIDES EFFECTIVE AGAINST MATRICARIA | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-09-25 | — | — | US | disclosed |
| JP-H0242076-A | 1-CHLOROPYRIMIDINYL-1H-1,2,4,-TRIAZOLE-3-SULFONAMIDE, ITS PRODUCTION, FORMULATION WITH HERBICIDAL ACTION CONTAINING THE COMPOUND AND PRODUCTION OF THE FORMULATION | SCHERING AG | 1990-02-13 | — | — | JP | disclosed |
| JP-H0242076-A | 1-CHLOROPYRIMIDINYL-1H-1,2,4,-TRIAZOLE-3-SULFONAMIDE, ITS PRODUCTION, FORMULATION WITH HERBICIDAL ACTION CONTAINING THE COMPOUND AND PRODUCTION OF THE FORMULATION | SCHERING AG | 1990-02-13 | — | — | JP | disclosed |
| EP-0338465-A1 | 1-Chloropyrimidinyl-1H-1,2,4-triazole-3-sulfonamides, process for their preparation and their use as agents with herbicidal activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-10-25 | — | — | EP | disclosed |