Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | JUN | P05412 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31138200 | 0.80 | NR1H2 (0.33) | RORC | |
| SCHEMBL28686868 | 0.73 | GRM4 (0.35) | LMNAMAPT | |
| SCHEMBL31138339 | 0.71 | PDE10A (0.38) | LMNAMAPT | |
| SCHEMBL31138165 | 0.71 | CD38 (0.47) | — | |
| SCHEMBL28313606 | 0.70 | LMNA (0.35) | MAPK10PDE4AJUNMAPK8LMNA | |
| SCHEMBL28059124 | 0.69 | KDM4E (0.43) | MAPK8LMNA | |
| SCHEMBL31138141 | 0.69 | IDH1 (0.32) | — | |
| SCHEMBL27841654 | 0.68 | HDAC8 (0.33) | LMNA | |
| SCHEMBL7494713 | 0.67 | MKNK2 (0.59) | — | |
| SCHEMBL28059065 | 0.67 | ADRB1 (0.52) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4685141-A1 | ISOINDOLINE DERIVATIVE, BENZOINDOLE DERIVATIVE AND USE THEREOF | Shanghai Helioson Pharmaceutical Co., Ltd. (CN) | 2026-01-28 | — | — | EP | disclosed |
| WO-2024193641-A1 | ISOINDOLINE DERIVATIVE, BENZOINDOLE DERIVATIVE AND USE THEREOF | 上海超阳药业有限公司 | 2024-09-26 | — | — | WO | disclosed |