Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527148 | 0.88 | KDM4E (0.33) | LMNAALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL9446238 | 0.79 | LMNA (0.40) | LMNAALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL9446210 | 0.78 | ALDH1A1 (0.40) | LMNAALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL9446207 | 0.75 | KDM4E (0.36) | LMNAALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL9446209 | 0.71 | LMNA (0.44) | LMNAALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL9526057 | 0.69 | ACACB (0.31) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL11133645 | 0.65 | PDE4D (0.51) | LMNAKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9446197 | 0.62 | ALDH1A1 (0.36) | LMNAALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL5513003 | 0.61 | NPSR1 (0.41) | LMNAALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL28804378 | 0.61 | ALDH1A1 (0.43) | LMNAALDH1A1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337263-B1 | ISOXAZOL(ISOTHIAZOLS)-5-CARBOXAMIDES | BASF Aktiengesellschaft (DE) | 1993-03-17 | — | — | EP | disclosed |
| EP-0337263-A2 | Isoxazol(isothiazols)-5-carboxamides | BASF Aktiengesellschaft (DE) | 1989-10-18 | — | — | EP | disclosed |