Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 11/20 | 0.40 |
| ▸ | GRK6 | P43250 | 3/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.32 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL954663 | 0.85 | MPO (0.40) | ICMTGRK6IDO1 | |
| SCHEMBL27557283 | 0.77 | CA2 (0.46) | — | |
| SCHEMBL1577056 | 0.76 | DGAT1 (0.45) | GRK6IDO1MAPK1CASP1 | |
| SCHEMBL10145320 | 0.73 | HSD17B10 (0.53) | — | |
| SCHEMBL23667636 | 0.73 | BTK (0.36) | GRK6MAPK1MAP2K4MAPKAPK2MAPKAPK3 | |
| SCHEMBL19457204 | 0.73 | TNIK (0.33) | GRK6 | |
| Hydrochloric Acid SCHEMBL952763 | 0.72 | HSD17B10 (0.51) | — | |
| SCHEMBL954662 | 0.72 | KCNH2 (0.30) | GRK6 | |
| SCHEMBL1482781 | 0.71 | RARB (0.42) | GRK6 | |
| SCHEMBL3647545 | 0.70 | FGFR1 (0.46) | GRK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |