Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 6/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | GRK6 | P43250 | 1/20 | 0.32 |
| ▸ | ICMT | O60725 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | SGK1 | O00141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL952671 | 0.85 | ICMT (0.40) | GRK6ICMTIDO1 | |
| SCHEMBL956333 | 0.78 | PLA2G10 (0.37) | MPOSPHK2 | |
| SCHEMBL949482 | 0.77 | MPO (0.36) | MPOSLC6A4 | |
| SCHEMBL1577056 | 0.72 | DGAT1 (0.45) | GRK6IDO1 | |
| SCHEMBL950000 | 0.72 | FFAR1 (0.39) | — | |
| SCHEMBL953932 | 0.71 | CAPN1 (0.34) | MPOSLC6A4 | |
| SCHEMBL10145320 | 0.70 | HSD17B10 (0.53) | — | |
| SCHEMBL23667636 | 0.69 | BTK (0.36) | GRK6 | |
| SCHEMBL19457204 | 0.69 | TNIK (0.33) | GRK6 | |
| SCHEMBL17672898 | 0.69 | HCAR2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |