Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 8/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | PTPRCAP | Q14761 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 9/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA6 | P23280 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946827 | 0.82 | CA1 (0.48) | CA1CA2CA4CA6 | |
| SCHEMBL9526776 | 0.82 | ADORA3 (0.43) | DRD1DRD2DRD5DRD3CA1 | |
| SCHEMBL9527460 | 0.81 | DRD1 (0.34) | DRD1HTR2CPTPRCAPDRD2DYRK1A | |
| SCHEMBL7849710 | 0.79 | MAPT (0.37) | DRD1HTR2CDRD2DRD5DRD3 | |
| SCHEMBL8524084 | 0.74 | MAPK8 (0.39) | DRD1DRD2DRD5DRD3CA1 | |
| SCHEMBL9528450 | 0.73 | CA1 (0.41) | DRD1DRD2DRD5DRD3CA1 | |
| SCHEMBL9526948 | 0.70 | CA1 (0.43) | DRD1DRD2DRD5DRD3CA1 | |
| SCHEMBL4377821 | 0.69 | DRD2 (0.56) | DRD1DRD2DRD5DRD3CA1 | |
| SCHEMBL9527310 | 0.68 | CA1 (0.37) | CA1CA2CA4CA6MAPK10 | |
| SCHEMBL9531330 | 0.68 | CA1 (0.49) | CA1CA2CA4CA6PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |