Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | DRD5 | P21918 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.32 |
| ▸ | WEE1 | P30291 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526783 | 0.82 | DRD1 (0.33) | MAPK8MAPK9MAPK10DRD2DRD1 | |
| SCHEMBL9527328 | 0.81 | CA1 (0.50) | ADORA3ADORA2ACHEK1CA1CA2 | |
| SCHEMBL9528233 | 0.78 | ALDH1A1 (0.32) | ADORA3DRD2DRD1DRD5DRD3 | |
| SCHEMBL8524084 | 0.76 | MAPK8 (0.39) | MAPK8MAPK9MAPK10DRD2DRD1 | |
| SCHEMBL7849710 | 0.73 | MAPT (0.37) | DRD2DRD1DRD5DRD3MEN1 | |
| SCHEMBL9526780 | 0.71 | DAO (0.41) | ADORA3ADORA2ADRD2DRD1DRD5 | |
| SCHEMBL3903939 | 0.69 | KDM4E (0.47) | MEN1ALDH1A1POLBGAAMAPT | |
| SCHEMBL9526738 | 0.69 | DAO (0.41) | DRD2DRD1DRD5DRD3ALDH1A1 | |
| SCHEMBL14963713 | 0.68 | MAOA (0.44) | MAPK8MAPK9MAPK10ALDH1A1MAPT | |
| SCHEMBL17434530 | 0.68 | USP8 (0.37) | MEN1ALDH1A1GAAKMT2ACHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |