Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD5 | P21918 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | MAP3K9 | P80192 | 2/20 | 0.35 |
| ▸ | MAP3K10 | Q02779 | 2/20 | 0.35 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528300 | 0.77 | DDB1 (0.34) | MAPK8MAPK9MAPK10CA1CA2 | |
| SCHEMBL9526776 | 0.76 | ADORA3 (0.43) | MAPK8MAPK9MAPK10CA1CA2 | |
| SCHEMBL7849710 | 0.76 | MAPT (0.37) | CA1CA2CA4CA6DRD2 | |
| SCHEMBL4374361 | 0.75 | CA1 (0.56) | CA1CA2CA4CA6DRD2 | |
| SCHEMBL29370154 | 0.75 | CA1 (0.56) | CA1CA2CA4CA6DRD2 | |
| SCHEMBL9526783 | 0.74 | DRD1 (0.33) | MAPK8MAPK9MAPK10CA1CA2 | |
| SCHEMBL14963713 | 0.73 | MAOA (0.44) | MAPK8MAPK9MAPK10CA1CA2 | |
| SCHEMBL3903939 | 0.71 | KDM4E (0.47) | CA1CA2CA4CA6KMT2A | |
| SCHEMBL599052 | 0.70 | MAOA (0.46) | MAPK8MAPK9CA1CA2DRD2 | |
| SCHEMBL29940783 | 0.67 | CA1 (0.50) | CA1CA2CA4CA6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952978-A1 | METALLOCENES AND CATALYSTS FOR OLEFIN-POLYMERISATION | Montell Technology Company bv (NL) | 1999-11-03 | — | — | EP | disclosed |
| WO-1999024446-A1 | METALLOCENES AND CATALYSTS FOR OLEFIN-POLYMERISATION | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1999-05-20 | — | — | WO | disclosed |