Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753352 | 0.82 | CYP3A4 (0.51) | ALDH1A1MAPTHTTCYP3A4TDP1 | |
| SCHEMBL9044256 | 0.81 | TDP1 (0.54) | ALDH1A1MAPTHTTCYP3A4TDP1 | |
| SCHEMBL2833356 | 0.81 | ALDH1A1 (0.57) | ALDH1A1MAPTSMN1; SMN2CYP3A4TDP1 | |
| SCHEMBL13753858 | 0.79 | POLB (0.59) | ALDH1A1MAPTHTTCYP3A4TDP1 | |
| SCHEMBL11068118 | 0.78 | ALDH1A1 (0.72) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7743774 | 0.78 | TDP1 (0.57) | ALDH1A1MAPTHTTSMN1; SMN2CYP3A4 | |
| SCHEMBL26757997 | 0.77 | MGLL (0.54) | ALDH1A1MAPTHTTSMN1; SMN2CYP3A4 | |
| SCHEMBL11064012 | 0.77 | CYP1A2 (0.70) | ALDH1A1SMN1; SMN2CYP3A4KMT2AMEN1 | |
| SCHEMBL30894817 | 0.76 | TDP1 (0.59) | ALDH1A1MAPTHTTCYP3A4TDP1 | |
| SCHEMBL6241415 | 0.76 | TDP1 (0.59) | ALDH1A1MAPTHTTCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285000-B1 | CHROMOGENE COMPOUNDS, THEIR MANUFACTURE AND USE AS ENZYME SUBSTRATES | Roche Diagnostics GmbH (DE) | 1993-07-28 | — | — | EP | disclosed |
| US-5190862-A | Peptide modified compound | BOEHRINGER MANNHEIM GMBH (DE) | 1993-03-02 | — | — | US | disclosed |
| US-5108890-A | Diagnostic agents for determining peptide bond-cleaving enzymes; measuring light absorbed by liberated colored materials | BOEHRINGER MANNHEIM GMBH (DE) | 1992-04-28 | — | — | US | disclosed |
| EP-0285000-A2 | Chromogene compounds, their manufacture and use as enzyme substrates | Roche Diagnostics GmbH (DE) | 1988-10-05 | — | — | EP | disclosed |