Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14523909 | 0.77 | RIPK1 (0.40) | KCNN4RIPK1ACHEKCNE1KCNQ1 | |
| SCHEMBL11621137 | 0.76 | KCNN4 (0.46) | KCNN4KCNE1KCNQ1POLBKIF11 | |
| SCHEMBL779068 | 0.76 | RIPK1 (0.39) | KCNN4RIPK1ACHEKCNE1KCNQ1 | |
| SCHEMBL27321412 | 0.76 | ACHE (0.37) | KCNN4RIPK1ACHEKCNE1KCNQ1 | |
| SCHEMBL11826461 | 0.75 | KCNN4 (0.45) | KCNN4RIPK1KCNE1KCNQ1HDAC3 | |
| SCHEMBL24826099 | 0.75 | KCNN4 (0.42) | KCNN4ACHEKCNE1KCNQ1ESR2 | |
| SCHEMBL17267041 | 0.75 | KCNN4 (0.42) | KCNN4ACHEKCNE1KCNQ1ESR2 | |
| SCHEMBL8583526 | 0.75 | KCNN4 (0.42) | KCNN4ACHEKCNE1KCNQ1ESR2 | |
| SCHEMBL3194195 | 0.74 | GABRA1 (0.48) | RIPK1ESR2TAS1R3TAS1R1HSD11B1 | |
| SCHEMBL2443511 | 0.74 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530207-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | Pfizer Limited (GB) | 1993-03-10 | — | — | EP | disclosed |