Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 14/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 9/20 | 0.41 |
| ▸ | GABRP | O00591 | 4/20 | 0.41 |
| ▸ | GABRD | O14764 | 4/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.41 |
| ▸ | GABRE | P78334 | 4/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411191 | 0.86 | BACE1 (0.39) | BACE1GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL10372959 | 0.81 | BACE1 (0.43) | BACE1GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9822782 | 0.81 | GABRB3 (0.45) | BACE1GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9526983 | 0.78 | BACE1 (0.41) | BACE1GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL10560567 | 0.78 | SMN1; SMN2 (0.43) | BACE1GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL10800915 | 0.77 | GABRB3 (0.43) | BACE1GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL10520101 | 0.77 | OXTR (0.43) | BACE1GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL10519709 | 0.76 | OXTR (0.47) | BACE1GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL5212709 | 0.75 | VNN1 (0.45) | BACE1GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL10400135 | 0.75 | BACE1 (0.42) | BACE1GABRB3GABRA2GABRB2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392241-B1 | SUBSTITUTED 1-ARYLPYRAZOLS | BAYER AG (DE) | 1993-06-02 | — | — | EP | disclosed |
| US-4971989-A | PESTICIDES, MITICIDES, INSECTICIDES AND NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-20 | — | — | US | disclosed |
| EP-0392241-A1 | Substituted 1-Arylpyrazols | BAYER AG (DE) | 1990-10-17 | — | — | EP | disclosed |