Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
| ▸ | XPO1 | O14980 | 1/20 | 0.30 |
| ▸ | MPL | P40238 | 2/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2747730 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTNPC1L3MBTL1MEN1 | |
| SCHEMBL7836861 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTNPC1L3MBTL1MEN1 | |
| SCHEMBL8086022 | 0.73 | ALDH1A1 (0.41) | ALDH1A1MAPTAHRMEN1KMT2A | |
| SCHEMBL2748682 | 0.71 | ALDH1A1 (0.42) | ALDH1A1AHRTRPV1HPGDHSD17B10 | |
| SCHEMBL799529 | 0.69 | ALDH1A1 (0.47) | ALDH1A1MAPTNPC1L3MBTL1MEN1 | |
| SCHEMBL6984166 | 0.69 | MAPT (0.44) | ALDH1A1MAPTNPC1L3MBTL1MEN1 | |
| SCHEMBL27795722 | 0.69 | ALDH1A1 (0.44) | ALDH1A1MAPTNPC1L3MBTL1MEN1 | |
| SCHEMBL17352453 | 0.68 | TTK (0.36) | ALDH1A1AHRTRPV1HSD17B10 | |
| SCHEMBL27993926 | 0.67 | ALDH1A1 (0.45) | ALDH1A1MAPTNPC1L3MBTL1MEN1 | |
| SCHEMBL6032151 | 0.67 | NPC1 (0.44) | MAPTNPC1L3MBTL1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533695-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY. | PFIZER (US) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991017163-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER INC. (US) | 1991-11-14 | — | — | WO | disclosed |