Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | DUT | P33316 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TK2 | O00142 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527858 | 1.00 | TK1 (0.40) | TK1CTSKALDH1A1KDM4EKIF11 | |
| SCHEMBL15827068 | 0.85 | MAPT (0.49) | TK1CTSKKIF11MAPTDUT | |
| SCHEMBL10411750 | 0.80 | SLC6A1 (0.39) | TK1ALDH1A1KDM4EKIF11 | |
| SCHEMBL2111572 | 0.80 | KIF11 (0.50) | TK1CTSKALDH1A1KIF11MAPT | |
| SCHEMBL3485608 | 0.77 | KIF11 (0.50) | TK1CTSKALDH1A1KDM4EKIF11 | |
| SCHEMBL19522241 | 0.77 | SLC6A1 (0.44) | TK1KIF11MAPT | |
| SCHEMBL9637986 | 0.76 | USP2 (0.47) | TK1CTSKALDH1A1KDM4EKIF11 | |
| SCHEMBL25243275 | 0.75 | USP2 (0.50) | TK1CTSKALDH1A1KDM4EKIF11 | |
| SCHEMBL2220171 | 0.75 | USP2 (0.50) | TK1CTSKALDH1A1KDM4EKIF11 | |
| SCHEMBL25289434 | 0.75 | USP2 (0.50) | TK1CTSKALDH1A1KDM4EKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238202-B1 | GLYCEROL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |