Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.63 |
| ▸ | LTA4H | P09960 | 2/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531948 | 0.89 | HRH3 (0.59) | LTA4HHRH3HRH1KCNH2 | |
| Hydrochloric Acid SCHEMBL9533399 | 0.81 | LTA4H (0.53) | LTA4HHRH3ALDH1A1TSHRACE2 | |
| SCHEMBL9528660 | 0.80 | LTA4H (0.62) | LTA4HHRH3TSHR | |
| SCHEMBL9531755 | 0.80 | KDM4E (0.56) | HRH3ALDH1A1TSHRKCNH2 | |
| Hydrochloric Acid SCHEMBL9530694 | 0.79 | LTA4H (0.61) | LTA4HHRH3TSHR | |
| SCHEMBL9528006 | 0.76 | HRH3 (0.55) | LTA4HHRH3ALDH1A1TSHR | |
| SCHEMBL21462645 | 0.75 | HRH3 (0.86) | BACE1LTA4HHRH3ALDH1A1HRH1 | |
| Hydrochloric Acid SCHEMBL9527673 | 0.74 | KMT2A (0.59) | HRH3ALDH1A1TSHR | |
| SCHEMBL18632545 | 0.74 | ALDH1A1 (0.46) | ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL9376586 | 0.74 | KMT2A (0.52) | LTA4HHRH3ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542844-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | claimed |