Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9376586 | 0.97 | KMT2A (0.52) | HRH3LMNALTA4HMEN1HTT | |
| Hydrochloric Acid SCHEMBL9527673 | 0.84 | KMT2A (0.59) | HRH3LMNAMEN1HTTKMT2A | |
| SCHEMBL9531948 | 0.84 | HRH3 (0.59) | HRH3LTA4HMEN1KMT2A | |
| SCHEMBL9528660 | 0.82 | LTA4H (0.62) | HRH3LTA4HPSMB1PSMB5TSHR | |
| Hydrochloric Acid SCHEMBL9530694 | 0.81 | LTA4H (0.61) | HRH3LTA4HPSMB1PSMB5TSHR | |
| Hydrochloric Acid SCHEMBL9706758 | 0.80 | MEN1 (0.44) | HRH3LMNALTA4HMEN1HTT | |
| Hydrochloric Acid SCHEMBL9528258 | 0.77 | HRH3 (0.60) | HRH3LMNALTA4HMEN1HTT | |
| SCHEMBL9527962 | 0.76 | BACE1 (0.63) | HRH3LTA4HALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL9533399 | 0.76 | LTA4H (0.53) | HRH3LMNALTA4HHTTKMT2A | |
| SCHEMBL9699167 | 0.76 | ALDH1A1 (0.45) | HRH3ALDH1A1THRBCACNA1HCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542844-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | claimed |