Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 13/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.61 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9530694 | 0.99 | LTA4H (0.61) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL9531948 | 0.88 | HRH3 (0.59) | LTA4HHRH3RAB9A | |
| SCHEMBL9528006 | 0.82 | HRH3 (0.55) | LTA4HHRH3PSMB1PSMB5TSHR | |
| Hydrochloric Acid SCHEMBL9527673 | 0.80 | KMT2A (0.59) | HRH3PSMB1PSMB5TSHR | |
| Hydrochloric Acid SCHEMBL9376586 | 0.80 | KMT2A (0.52) | LTA4HHRH3PSMB1PSMB5TSHR | |
| SCHEMBL9527962 | 0.80 | BACE1 (0.63) | LTA4HHRH3TSHR | |
| SCHEMBL18854867 | 0.78 | ALDH1A1 (0.47) | LTA4H | |
| SCHEMBL7141103 | 0.77 | LTA4H (1.00) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL7133844 | 0.77 | LTA4H (1.00) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL8637452 | 0.76 | HRH3 (1.00) | LTA4HHRH3PSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542844-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | claimed |