Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528098 | 0.92 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL9407505 | 0.80 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9528273 | 0.78 | KMT2A (0.52) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL9407487 | 0.77 | CTSK (0.46) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL17550873 | 0.76 | RAB9A (0.59) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL7998297 | 0.75 | RAB9A (0.60) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL9407494 | 0.74 | GAA (0.58) | NPC1RAB9ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL21595963 | 0.74 | MEN1 (0.61) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL10876260 | 0.74 | MEN1 (0.54) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL17864863 | 0.74 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |