Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524767 | 0.82 | LMNA (0.53) | LMNANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9525271 | 0.82 | NPC1 (0.52) | LMNANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9526235 | 0.81 | LMNA (0.49) | LMNANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9524940 | 0.74 | NPC1 (0.44) | LMNANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9525983 | 0.74 | NPC1 (0.46) | LMNANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9526055 | 0.73 | HSD17B10 (0.47) | LMNANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9525375 | 0.73 | NPC1 (0.45) | LMNANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9525465 | 0.73 | NPC1 (0.47) | LMNANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9525255 | 0.73 | KDM4E (0.44) | ALDH1A1SMN1; SMN2KDM4EHPGDPOLB | |
| SCHEMBL9524147 | 0.73 | KDM4E (0.44) | LMNANPC1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |