Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702630 | 0.89 | LMNA (0.54) | KDM4ELMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL615999 | 0.82 | KDM4E (0.72) | KDM4ELMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL30480747 | 0.82 | KDM4E (0.72) | KDM4ELMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5546782 | 0.82 | LMNA (0.56) | KDM4ELMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9374466 | 0.80 | LMNA (0.55) | KDM4ELMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL17231059 | 0.79 | LMNA (0.60) | KDM4ELMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9373776 | 0.78 | LMNA (0.47) | KDM4ELMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3944765 | 0.77 | LIG1 (0.54) | KDM4ELMNASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL9376948 | 0.77 | LMNA (0.46) | KDM4ELMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL810987 | 0.77 | KMT2A (0.51) | KDM4ELMNAALDH1A1MAPTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |