Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4516770 | 0.89 | ALDH1A1 (0.61) | ALDH1A1KMT2ASRD5A2LMNAMAPT | |
| SCHEMBL10699004 | 0.87 | LMNA (0.62) | ALDH1A1KMT2ASRD5A2LMNAMAPT | |
| SCHEMBL24186223 | 0.85 | LTA4H (0.52) | ALDH1A1LMNAMAPTHPGDHTT | |
| SCHEMBL3590906 | 0.85 | SRD5A2 (0.55) | ALDH1A1KMT2ASRD5A2HPGDHTT | |
| SCHEMBL2720045 | 0.85 | ALDH1A1 (0.64) | ALDH1A1KMT2ASRD5A2LMNAHPGD | |
| SCHEMBL24404194 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KMT2ACAPN1SIRT2 | |
| SCHEMBL153032 | 0.81 | — | — | |
| SCHEMBL2889586 | 0.81 | — | — | |
| SCHEMBL24185778 | 0.80 | CA2 (0.48) | ALDH1A1LMNAMAPTESR1HTT | |
| SCHEMBL14143387 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KMT2ASRD5A2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544705-A1 | DERIVATIVES OF MUPIROCIN | Beecham Group p.l.c. (GB) | 1993-06-09 | — | — | EP | disclosed |
| WO-1992002518-A1 | DERIVATIVES OF MUPIROCIN | BEECHAM GROUP PLC (GB) | 1992-02-20 | — | — | WO | disclosed |
| US-4935440-A | ANALGESICS, ANTIPYRETICS | SYNTEX (U.S.A.) INC. (US) | 1990-06-19 | — | — | US | disclosed |
| US-4833155-A | SKIN DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1989-05-23 | — | — | US | disclosed |
| EP-0269981-A1 | 3-[alpha-(3,5-di-t-butyl-4-hydroxyphenyl)-alkanoyl]pyrroles, their de-oxy analogs, and therapeutic uses thereof | SYNTEX (U.S.A.) INC. (US) | 1988-06-08 | — | — | EP | disclosed |