Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 17/20 | 0.49 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.46 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528603 | 1.00 | CYP19A1 (0.50) | CYP19A1CYP11B2TBXAS1PLOD2PLOD3 | |
| SCHEMBL4535241 | 0.89 | SIGMAR1 (0.47) | TBXAS1TBXA2R | |
| SCHEMBL9524284 | 0.81 | L3MBTL1 (0.46) | CYP19A1CYP11B2TBXAS1ALDH1A1CYP1A2 | |
| SCHEMBL9524288 | 0.81 | L3MBTL1 (0.46) | CYP19A1CYP11B2TBXAS1ALDH1A1CYP1A2 | |
| SCHEMBL6419131 | 0.79 | CYP19A1 (0.55) | CYP19A1CYP11B2TBXAS1PLOD2PLOD3 | |
| SCHEMBL6419179 | 0.79 | CYP19A1 (0.55) | CYP19A1CYP11B2TBXAS1PLOD2PLOD3 | |
| SCHEMBL8216126 | 0.77 | SIGMAR1 (0.53) | TBXAS1TBXA2R | |
| SCHEMBL8511316 | 0.77 | SIGMAR1 (0.53) | TBXAS1TBXA2R | |
| SCHEMBL9092744 | 0.76 | SIGMAR1 (0.53) | TBXAS1TBXA2R | |
| SCHEMBL3026802 | 0.75 | CYP19A1 (0.59) | CYP19A1CYP11B2PLOD2PLOD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231996-B1 | NOVEL AMINO ACID DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-10-06 | — | — | EP | disclosed |
| US-4931450-A | Amino acid derivatives | NOVO INDUSTRI A/S (DK) | 1990-06-05 | — | — | US | disclosed |