Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528711 | 1.00 | ALDH1A1 (0.51) | ALDH1A1POLBRECQLSMN1; SMN2HIF1A | |
| SCHEMBL9531042 | 0.83 | L3MBTL1 (0.43) | ALDH1A1POLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7969659 | 0.83 | ALDH1A1 (0.46) | ALDH1A1POLBRECQLSMN1; SMN2HIF1A | |
| SCHEMBL7007267 | 0.83 | ALDH1A1 (0.46) | ALDH1A1POLBRECQLSMN1; SMN2HIF1A | |
| SCHEMBL9531037 | 0.83 | L3MBTL1 (0.43) | ALDH1A1POLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2088416 | 0.80 | ALDH1A1 (0.46) | ALDH1A1POLBKMT2AGAAMAPT | |
| SCHEMBL9532178 | 0.80 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL9532175 | 0.80 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL3455076 | 0.79 | POLB (0.52) | ALDH1A1POLBRECQLSMN1; SMN2EGFR | |
| SCHEMBL3455077 | 0.79 | POLB (0.52) | ALDH1A1POLBRECQLSMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536424-A1 | NOVEL BENZOPYRAN DERIVATIVE | Japan Tobacco Inc. (JP) | 1993-04-14 | — | — | EP | disclosed |