Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532175 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL3455077 | 0.81 | POLB (0.52) | SMN1; SMN2ALDH1A1LMNATDP1L3MBTL1 | |
| SCHEMBL3455076 | 0.81 | POLB (0.52) | SMN1; SMN2ALDH1A1LMNATDP1L3MBTL1 | |
| SCHEMBL7972363 | 0.81 | ALDH1A1 (0.35) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL7972359 | 0.81 | ALDH1A1 (0.35) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL9528711 | 0.80 | ALDH1A1 (0.51) | SMN1; SMN2CYP2C19ALDH1A1CYP3A4KDM4E | |
| SCHEMBL9528709 | 0.80 | ALDH1A1 (0.51) | SMN1; SMN2CYP2C19ALDH1A1CYP3A4KDM4E | |
| SCHEMBL9217151 | 0.78 | CA2 (0.41) | ALDH1A1LMNAKDM4EGAAMAPT | |
| SCHEMBL30827437 | 0.78 | GSK3B (0.40) | SMN1; SMN2CYP1A2ALDH1A1CYP2C9CYP2D6 | |
| SCHEMBL9217149 | 0.78 | CA2 (0.41) | ALDH1A1LMNAKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536424-A1 | NOVEL BENZOPYRAN DERIVATIVE | Japan Tobacco Inc. (JP) | 1993-04-14 | — | — | EP | disclosed |