Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530426 | 0.83 | TSHR (0.41) | PGRMGLLSAE1UBA2RORC | |
| SCHEMBL9532523 | 0.83 | TSHR (0.41) | PGRMGLLSAE1UBA2RORC | |
| SCHEMBL9529430 | 0.83 | TSHR (0.41) | PGRMGLLSAE1UBA2RORC | |
| SCHEMBL9529425 | 0.83 | TSHR (0.41) | PGRMGLLSAE1UBA2RORC | |
| SCHEMBL10452606 | 0.83 | TSHR (0.41) | PGRMGLLSAE1UBA2RORC | |
| SCHEMBL15480393 | 0.77 | PGR (0.65) | PGRRORCTHRATHRBNAMPT | |
| SCHEMBL20777973 | 0.77 | PGR (0.65) | PGRRORCTHRATHRBNAMPT | |
| SCHEMBL10453701 | 0.77 | ABCC9 (0.46) | SAE1UBA2MAPTMEN1ALDH1A1 | |
| SCHEMBL9530006 | 0.74 | PGR (0.46) | PGRMGLLSAE1UBA2MAPT | |
| SCHEMBL10453694 | 0.74 | MAPT (0.41) | SAE1UBA2MAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |