Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529425 | 1.00 | TSHR (0.41) | TSHRHSD17B10ABCC9KCNJ11MGLL | |
| SCHEMBL9532523 | 1.00 | TSHR (0.41) | TSHRHSD17B10ABCC9KCNJ11MGLL | |
| SCHEMBL9529430 | 1.00 | TSHR (0.41) | TSHRHSD17B10ABCC9KCNJ11MGLL | |
| SCHEMBL10452606 | 1.00 | TSHR (0.41) | TSHRHSD17B10ABCC9KCNJ11MGLL | |
| SCHEMBL9528767 | 0.83 | PGR (0.44) | TSHRMGLLPGRSAE1UBA2 | |
| SCHEMBL10453701 | 0.83 | ABCC9 (0.46) | TSHRABCC9KCNJ11SAE1UBA2 | |
| SCHEMBL10453762 | 0.80 | ABCC9 (0.45) | TSHRABCC9KCNJ11SAE1UBA2 | |
| SCHEMBL9530625 | 0.77 | MAOA (0.44) | ABCC9KCNJ11SAE1UBA2LMNA | |
| SCHEMBL10453470 | 0.75 | ABCC9 (0.65) | TSHRABCC9KCNJ11SAE1UBA2 | |
| SCHEMBL8915586 | 0.75 | ABCC9 (0.46) | TSHRABCC9KCNJ11SAE1UBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |