Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529601 | 0.85 | SLC2A1 (0.42) | L3MBTL1SIRT2MAOBAOC3KDM4E | |
| SCHEMBL9529150 | 0.84 | CYP4F2 (0.41) | L3MBTL1KDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL9531938 | 0.83 | TBXA2R (0.46) | L3MBTL1SIRT2KMT2A | |
| SCHEMBL9529710 | 0.78 | RAB9A (0.44) | L3MBTL1KDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL9528779 | 0.78 | KDM4E (0.44) | TLR7KDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL9528881 | 0.74 | TBXA2R (0.52) | L3MBTL1TLR7 | |
| SCHEMBL17842328 | 0.73 | TLR7 (0.60) | L3MBTL1TLR7ALDH1A1KMT2ALMNA | |
| SCHEMBL17842331 | 0.73 | TLR7 (0.60) | L3MBTL1TLR7ALDH1A1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL11447923 | 0.72 | L3MBTL1 (0.52) | L3MBTL1KDM4EALDH1A1MCL1LMNA | |
| SCHEMBL23366565 | 0.69 | KDM4E (0.49) | L3MBTL1KDM4EALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |