Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529150 | 0.90 | CYP4F2 (0.41) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9529710 | 0.88 | RAB9A (0.44) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9529174 | 0.83 | LTA4H (0.39) | KMT2ARAB9ANPC1SMN1; SMN2CYP4F2 | |
| SCHEMBL9529148 | 0.81 | GLA (0.45) | MEN1KMT2ANPC1SMN1; SMN2CYP4F2 | |
| SCHEMBL9530012 | 0.80 | KDM4E (0.42) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9528880 | 0.78 | L3MBTL1 (0.41) | KDM4EKMT2AALDH1A1LMNATLR7 | |
| SCHEMBL9529562 | 0.74 | KDM4E (0.42) | KDM4ERAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL23366565 | 0.74 | KDM4E (0.49) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9527584 | 0.73 | LMNA (0.43) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL20658449 | 0.72 | RAB9A (0.55) | KDM4EMEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0366006-A1 | Pyridylketoxime ether compound and pharmaceutical composition containing it | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |