Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528779 | 0.90 | KDM4E (0.44) | CYP4F2CYP4A11KDM4ESMN1; SMN2LMNA | |
| SCHEMBL9529710 | 0.90 | RAB9A (0.44) | CYP4F2CYP4A11KDM4ESMN1; SMN2LMNA | |
| SCHEMBL9528880 | 0.84 | L3MBTL1 (0.41) | KDM4ELMNAKMT2AHTTALDH1A1 | |
| SCHEMBL9527584 | 0.82 | LMNA (0.43) | CYP4F2CYP4A11KDM4ESMN1; SMN2LMNA | |
| SCHEMBL9530556 | 0.79 | MAPT (0.43) | CYP4F2CYP4A11SMN1; SMN2LMNAKMT2A | |
| SCHEMBL9532029 | 0.78 | KDM4E (0.42) | KDM4ESMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL23366565 | 0.77 | KDM4E (0.49) | KDM4ESMN1; SMN2LMNAHPGDNPSR1 | |
| SCHEMBL9529562 | 0.75 | KDM4E (0.42) | KDM4ESMN1; SMN2LMNAHTTNPC1 | |
| SCHEMBL9528883 | 0.73 | NPC1 (0.43) | KDM4ESMN1; SMN2LMNAHPGDMEN1 | |
| SCHEMBL9529174 | 0.73 | LTA4H (0.39) | CYP4F2CYP4A11SMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0366006-A1 | Pyridylketoxime ether compound and pharmaceutical composition containing it | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |