Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529668 | 0.90 | KDM4E (0.47) | GAAKDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL9528579 | 0.83 | ALDH1A1 (0.53) | GAAKDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL9528361 | 0.83 | ALDH1A1 (0.50) | KDM4EMAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL9529147 | 0.82 | NOTUM (0.44) | GAAMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9532147 | 0.79 | CYP1A2 (0.44) | GAAMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10406927 | 0.79 | ALDH1A1 (0.44) | MAPTALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL9528143 | 0.79 | CYP1A2 (0.42) | KDM4EMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9529168 | 0.79 | ALDH1A1 (0.45) | GAAKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL9527614 | 0.79 | EPHX2 (0.48) | GAAKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9527670 | 0.79 | EPHX2 (0.48) | KDM4EALDH1A1LMNASMN1; SMN2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| EP-0366006-A1 | Pyridylketoxime ether compound and pharmaceutical composition containing it | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |