Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 11/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 10/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530560 | 0.91 | TBXAS1 (0.58) | TBXAS1TBXA2RALDH1A1MAPT | |
| SCHEMBL9529177 | 0.89 | ALDH1A1 (0.52) | TBXAS1TBXA2RPSEN1PSEN2APH1B | |
| SCHEMBL9529764 | 0.88 | TBXAS1 (0.56) | TBXAS1TBXA2RALDH1A1NPC1POLB | |
| SCHEMBL9528785 | 0.81 | KDM4E (0.55) | TBXAS1TBXA2RALDH1A1NPC1MAPT | |
| SCHEMBL9527696 | 0.81 | TBXAS1 (0.52) | TBXAS1GLATBXA2RALDH1A1NPC1 | |
| SCHEMBL9527590 | 0.79 | ALDH1A1 (0.58) | TBXAS1TBXA2RALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8805695 | 0.78 | TBXAS1 (0.56) | TBXAS1TBXA2RALDH1A1MAPT | |
| SCHEMBL8805691 | 0.78 | TBXAS1 (0.56) | TBXAS1TBXA2RALDH1A1MAPT | |
| SCHEMBL9531940 | 0.78 | TBXA2R (0.65) | TBXAS1TBXA2R | |
| SCHEMBL5429070 | 0.77 | TBXAS1 (0.52) | TBXAS1TBXA2RALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |