Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530809 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDHTTKDM4E | |
| SCHEMBL9529674 | 0.80 | TBXAS1 (0.48) | ALDH1A1MAPTHPGDKDM4EGAA | |
| SCHEMBL1796749 | 0.80 | NPC1 (0.53) | ALDH1A1MAPTHPGDKDM4ENPC1 | |
| SCHEMBL1796753 | 0.80 | NPC1 (0.53) | ALDH1A1MAPTHPGDKDM4ENPC1 | |
| SCHEMBL8289135 | 0.80 | NPC1 (0.53) | ALDH1A1MAPTHPGDKDM4ENPC1 | |
| SCHEMBL9529568 | 0.79 | KDM4E (0.51) | ALDH1A1MAPTHPGDKDM4ENPC1 | |
| SCHEMBL9567506 | 0.76 | KDM4E (0.58) | ALDH1A1MAPTHPGDKDM4EGAA | |
| SCHEMBL9567509 | 0.76 | KDM4E (0.58) | ALDH1A1MAPTHPGDKDM4EGAA | |
| SCHEMBL9532057 | 0.74 | NPC1 (0.54) | ALDH1A1MAPTHPGDHTTKDM4E | |
| SCHEMBL9530015 | 0.74 | KDM4E (0.57) | ALDH1A1MAPTHPGDKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |