Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529674 | 0.88 | TBXAS1 (0.48) | ALDH1A1SMN1; SMN2HPGDCYP1A2CYP2D6 | |
| SCHEMBL9529284 | 0.83 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EMAPTMAPK1 | |
| SCHEMBL10407005 | 0.78 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2HPGDCYP1A2CYP2D6 | |
| SCHEMBL9529952 | 0.76 | TBXAS1 (0.52) | ALDH1A1SMN1; SMN2KMT2AKDM4EMAPT | |
| SCHEMBL9529026 | 0.73 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2HPGDCYP1A2CYP2D6 | |
| SCHEMBL14667503 | 0.73 | MEN1 (0.47) | CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL10406690 | 0.72 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2HPGDCYP1A2CYP2D6 | |
| SCHEMBL9528119 | 0.72 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2HPGDCYP1A2CYP2D6 | |
| SCHEMBL9528177 | 0.72 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2HPGDCYP1A2CYP2D6 | |
| SCHEMBL10407326 | 0.70 | CYP2C19 (0.47) | ALDH1A1SMN1; SMN2HPGDCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |