Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 2/20 | 0.61 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.61 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.61 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529336 | 0.78 | OPRL1 (0.57) | OPRM1OPRL1SIGMAR1POLBDRD2 | |
| SCHEMBL31028225 | 0.78 | SLC6A1 (0.61) | SLC6A1SLC6A12SLC6A11SLC6A13OPRM1 | |
| SCHEMBL4293184 | 0.76 | SLC6A1 (1.00) | SLC6A1SLC6A12SLC6A11SLC6A13OPRM1 | |
| SCHEMBL29462287 | 0.76 | SLC6A1 (1.00) | SLC6A1SLC6A12SLC6A11SLC6A13OPRM1 | |
| SCHEMBL31028218 | 0.76 | CHRM4 (0.64) | SLC6A1SLC6A12SLC6A11SLC6A13OPRM1 | |
| SCHEMBL2970071 | 0.76 | CHRM4 (0.64) | SLC6A1SLC6A12SLC6A11SLC6A13OPRM1 | |
| Hydrochloric Acid SCHEMBL30286393 | 0.75 | SLC6A1 (0.98) | SLC6A1SLC6A12SLC6A11SLC6A13OPRM1 | |
| Hydrochloric Acid SCHEMBL8178596 | 0.75 | SLC6A1 (0.98) | SLC6A1SLC6A12SLC6A11SLC6A13OPRM1 | |
| SCHEMBL5592141 | 0.74 | SLC6A1 (0.65) | SLC6A1SLC6A12SLC6A11SLC6A13OPRM1 | |
| SCHEMBL9053004 | 0.73 | DRD2 (0.67) | SLC6A1SLC6A12SLC6A11SLC6A13SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | disclosed |