Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741960 | 0.94 | OPRL1 (0.55) | OPRL1SIGMAR1POLBDRD2KCNA3 | |
| SCHEMBL9533670 | 0.86 | DRD2 (0.60) | OPRL1DRD2OPRM1CCR3CCR1 | |
| SCHEMBL9529535 | 0.86 | DRD2 (0.60) | SIGMAR1DRD2OPRM1 | |
| SCHEMBL9528489 | 0.78 | CCR1 (0.50) | OPRL1SIGMAR1DRD2MEN1KMT2A | |
| SCHEMBL17592683 | 0.78 | OPRL1 (0.49) | OPRL1SIGMAR1POLBDRD2KCNA3 | |
| SCHEMBL9529302 | 0.78 | SLC6A1 (0.61) | OPRL1SIGMAR1POLBDRD2MEN1 | |
| SCHEMBL24489451 | 0.76 | OPRL1 (0.65) | OPRL1SIGMAR1POLBDRD2KCNA3 | |
| SCHEMBL1307928 | 0.76 | OPRL1 (0.65) | OPRL1SIGMAR1POLBDRD2KCNA3 | |
| SCHEMBL2059079 | 0.76 | OPRL1 (0.68) | OPRL1SIGMAR1POLBDRD2KCNA3 | |
| SCHEMBL9370237 | 0.75 | SIGMAR1 (0.72) | OPRL1SIGMAR1POLBDRD2KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | disclosed |