Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | MGMT | P16455 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431905 | 0.76 | LTA4H (0.44) | MAPTL3MBTL1CDC7DBF4MAPK1 | |
| SCHEMBL1486448 | 0.76 | DCPS (0.60) | CDC7DBF4IDO1LTA4HPLA2G2A | |
| SCHEMBL8486078 | 0.75 | KDM4E (0.48) | MAPK1LTA4HPLA2G2ATRPM8SMN1; SMN2 | |
| SCHEMBL8284793 | 0.75 | IDO1 (0.37) | IDO1SMN1; SMN2DRD2RAB9A | |
| SCHEMBL11784078 | 0.75 | PDE5A (0.47) | CYP1A2CDK1CYP2C9CCNB1CCNA2 | |
| SCHEMBL8130860 | 0.75 | PARP1 (0.36) | CDC7DBF4IDO1SMN1; SMN2DRD2 | |
| SCHEMBL7280673 | 0.74 | NCF1 (0.36) | MAPTIDO1NFKB1SMN1; SMN2DRD2 | |
| SCHEMBL9529342 | 0.74 | DRD4 (0.64) | MAPTL3MBTL1CDC7DBF4MAPK1 | |
| SCHEMBL3082549 | 0.74 | ABL1 (0.54) | MAPTL3MBTL1DCPSLMNATSHR | |
| SCHEMBL7619113 | 0.74 | L3MBTL1 (0.54) | MAPTL3MBTL1MAPK1TDP1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266326-B1 | NOVEL DERIVATIVES OF BENZIMIDAZOLES ACTIVE AS ANTI-ULCER AGENTS | Aktiebolaget Hässle (SE) | 1993-03-10 | — | — | EP | disclosed |
| US-5106862-A | DERIVATIVES OF BENZIMIDAZOLES ACTIVE AS ANTI-ULCER AGENTS | AKTIEBOLAGET HASSLE (SE) | 1992-04-21 | — | — | US | disclosed |