Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28468299 | 0.88 | ZDHHC7 (0.44) | ZDHHC7CPB2L3MBTL1MAPTKMT2A | |
| SCHEMBL7069715 | 0.76 | ZDHHC7 (0.43) | ZDHHC7CPB2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL7077005 | 0.76 | ZDHHC7 (0.43) | ZDHHC7CPB2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL8436602 | 0.75 | ALDH1A1 (0.37) | ALDH1A1TRPA1TDP1TSHRCYP3A4 | |
| SCHEMBL29119233 | 0.74 | FAAH (0.44) | ZDHHC7ALDH1A1TSHRMAPT | |
| SCHEMBL29119376 | 0.74 | FAAH (0.44) | ZDHHC7ALDH1A1TSHRMAPT | |
| SCHEMBL29119365 | 0.74 | FAAH (0.44) | ZDHHC7ALDH1A1TSHRMAPT | |
| SCHEMBL29119278 | 0.74 | FAAH (0.44) | ZDHHC7ALDH1A1TSHRMAPT | |
| SCHEMBL29119069 | 0.74 | FAAH (0.44) | ZDHHC7ALDH1A1TSHRMAPT | |
| SCHEMBL29064892 | 0.74 | CPB2 (0.37) | CPB2ALDH1A1TDP1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550502-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992004330-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-03-19 | — | — | WO | disclosed |