Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29064892 | 0.83 | CPB2 (0.37) | ALDH1A1ALOX15CYP3A4TSHRTDP1 | |
| SCHEMBL28468299 | 0.78 | ZDHHC7 (0.44) | — | |
| SCHEMBL28019693 | 0.76 | ALDH1A1 (0.39) | ALDH1A1ALOX15CYP3A4TSHRTDP1 | |
| SCHEMBL6332192 | 0.75 | ALDH1A1 (0.37) | ALDH1A1TDP1 | |
| SCHEMBL9529396 | 0.75 | ZDHHC7 (0.35) | ALDH1A1ALOX15CYP3A4TSHRTDP1 | |
| SCHEMBL27884848 | 0.74 | ALDH1A1 (0.38) | ALDH1A1ALOX15CYP3A4TSHRTDP1 | |
| SCHEMBL28738774 | 0.74 | ALDH1A1 (0.38) | ALDH1A1ALOX15CYP3A4TSHRTDP1 | |
| SCHEMBL27701810 | 0.74 | MMP8 (0.50) | ALDH1A1TSHRGAARAB9A | |
| SCHEMBL16558630 | 0.74 | ALDH1A1 (0.39) | ALDH1A1ALOX15CYP3A4TSHRTDP1 | |
| SCHEMBL28138974 | 0.72 | ALDH1A1 (0.39) | ALDH1A1ALOX15CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916898-A | ANTIFIBROPROLIFERTIVE, ENZYME INHIBITORS OF PYROLYL 4-HYDROXYLASE, ANTIARTHRITIC AGENTS | ZENECA LIMITED (GB) | 1999-06-29 | — | — | US | disclosed |