Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676621 | 0.84 | ALDH1A1 (0.43) | BCHEKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL27543142 | 0.73 | KDM1A (0.41) | KDM4EMEN1ALDH1A1POLBHPGD | |
| SCHEMBL5830749 | 0.72 | BCHE (0.61) | BCHEATMSIGMAR1NPSR1SLC18A2 | |
| SCHEMBL8003845 | 0.72 | KDM4E (0.45) | KDM4EMEN1ALDH1A1POLBHPGD | |
| SCHEMBL3247866 | 0.71 | ALDH1A1 (0.43) | KDM4EMEN1ALDH1A1POLBHPGD | |
| SCHEMBL497987 | 0.71 | KDM1A (0.39) | KDM4EALDH1A1POLBSIGMAR1NPSR1 | |
| SCHEMBL108120 | 0.71 | CHAT (0.43) | KDM4EALDH1A1CNR1 | |
| SCHEMBL5477082 | 0.71 | RXRA (0.41) | KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL7795350 | 0.70 | RXRA (0.43) | KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL9529506 | 0.70 | BCHE (0.66) | BCHEATMSIGMAR1NPSR1SLC18A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531382-A1 | N-SUBSTITUTED-1,2,4-TRIAZOLONE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1993-03-17 | — | — | EP | disclosed |