Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HPGDS | O60760 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530946 | 0.81 | MME (0.36) | PDE2AMMEALDH1A1SMN1; SMN2 | |
| SCHEMBL7598651 | 0.74 | TSHR (0.47) | HDAC3HDAC4HDAC1HDAC6ALDH1A1 | |
| SCHEMBL10666410 | 0.73 | ALDH1A1 (0.54) | ALDH1A1LMNASMN1; SMN2CTSS | |
| SCHEMBL9529998 | 0.73 | MME (0.36) | MME | |
| SCHEMBL9848415 | 0.73 | LMNA (0.53) | HDAC1HPGDSALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7067325 | 0.72 | ALDH1A1 (0.47) | PDE2AALDH1A1LMNASMN1; SMN2CTSS | |
| SCHEMBL14065364 | 0.71 | ALDH1A1 (0.53) | ALDH1A1CTSSAKR1C3AKR1C1 | |
| SCHEMBL15716728 | 0.68 | CTSS (0.51) | ALDH1A1SMN1; SMN2CTSSAKR1C3AKR1C1 | |
| SCHEMBL10705514 | 0.68 | CTSS (0.50) | ALDH1A1SMN1; SMN2CTSS | |
| SCHEMBL11639107 | 0.68 | TSHR (0.44) | PDE2AHDAC3HDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313091-B1 | AMIDE DERIVATIVES, PROCESSES FOR PRODUCTION THEREOF, AND AGRICULTURAL-HORTICULTURAL FUNGICIDE CONTAINING THEM | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-09-01 | — | — | EP | disclosed |
| CN-1066363-A | MICROBICIDES COMPOSITION FOR AGRICULTURE-HORTICULTURE | MITSUI TOATSU CHEMICALS (JP) | 1992-11-25 | — | — | CN | disclosed |
| CN-1018828-B | Process for preparing thiazole or isothiazole amide derivatives | MITSUI TOATSU CHEMICALS (JP) | 1992-10-28 | — | — | CN | disclosed |
| US-5104886-A | Syntergistic mixtures of amide substituted thiazoles and other fungicides | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-04-14 | — | — | US | disclosed |
| US-4980363-A | CONTROLLING PLANT DISEASES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1990-12-25 | — | — | US | disclosed |
| CN-1035826-A | Novel amide derivative and agricultural-horticultural fungicide containing the same | MITSUI TOATSU CHEMICALS (JP) | 1989-09-27 | — | — | CN | disclosed |
| EP-0313091-A2 | Amide derivatives, processes for production thereof, and agricultural-horticultural fungicide containing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-04-26 | — | — | EP | disclosed |