Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527518 | 0.86 | LTA4H (0.61) | LTA4HHRH3SLC6A4KMT2A | |
| SCHEMBL11244902 | 0.83 | LTA4H (0.81) | LTA4HHRH3KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL14970473 | 0.83 | LTA4H (0.81) | LTA4HHRH3KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL9532095 | 0.82 | LTA4H (0.58) | LTA4HHRH3KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL9529137 | 0.82 | HRH3 (0.63) | LTA4HHRH3KDM4EALDH1A1SLC6A4 | |
| Hydrochloric Acid SCHEMBL14969107 | 0.82 | LTA4H (0.79) | LTA4HHRH3KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL9530966 | 0.78 | HRH3 (0.76) | HRH3KDM4E | |
| SCHEMBL9528301 | 0.77 | HRH3 (0.68) | LTA4HHRH3ALDH1A1SLC6A4KMT2A | |
| SCHEMBL7915852 | 0.77 | LTA4H (0.67) | LTA4HHRH3KDM4EALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL9527233 | 0.77 | HRH3 (0.74) | HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542846-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | claimed |