Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 11/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 9/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532300 | 0.85 | TBXAS1 (0.57) | ALDH1A1TBXAS1TBXA2RTAAR1KDM4E | |
| SCHEMBL9601603 | 0.84 | TBXAS1 (0.64) | ALDH1A1L3MBTL1TBXAS1TBXA2R | |
| SCHEMBL9601617 | 0.84 | TBXAS1 (0.64) | ALDH1A1L3MBTL1TBXAS1TBXA2R | |
| SCHEMBL9528581 | 0.84 | TBXAS1 (0.59) | ALDH1A1TBXAS1TBXA2RTAAR1KDM4E | |
| SCHEMBL9528023 | 0.84 | SMN1; SMN2 (0.48) | ALDH1A1TBXAS1TBXA2RTAAR1KDM4E | |
| SCHEMBL9531922 | 0.84 | TBXAS1 (0.52) | ALDH1A1TBXAS1TBXA2RTAAR1KDM4E | |
| SCHEMBL9529952 | 0.81 | TBXAS1 (0.52) | ALDH1A1L3MBTL1TBXAS1TBXA2RKDM4E | |
| SCHEMBL9531103 | 0.81 | TBXAS1 (0.50) | ALDH1A1TBXAS1TBXA2RTAAR1KDM4E | |
| SCHEMBL9529953 | 0.81 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1TBXAS1TBXA2RTAAR1 | |
| SCHEMBL9528066 | 0.81 | TBXAS1 (0.53) | ALDH1A1TBXAS1TBXA2RTAAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0366006-A1 | Pyridylketoxime ether compound and pharmaceutical composition containing it | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |