Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10559305 | 0.87 | DRD2 (0.42) | NR3C2MAPK14SLC6A2SLC6A4DRD2 | |
| SCHEMBL9527650 | 0.84 | NR3C2 (0.49) | NR3C2MAPK14ADRA2AHTR1AMAOB | |
| SCHEMBL16385859 | 0.83 | NR3C2 (0.43) | NR3C2MAPK14ADRA2ASLC6A2SLC6A4 | |
| SCHEMBL5400526 | 0.81 | HTR2A (0.44) | DRD2DRD3MAOB | |
| SCHEMBL9528836 | 0.81 | TERT (0.42) | SLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL10444469 | 0.79 | NR3C2 (0.41) | NR3C2MAPK14SLC6A2SLC6A4HTR2B | |
| SCHEMBL11277012 | 0.74 | HTR2B (0.40) | MAPK14ADRA2ASLC6A2SLC6A4HTR2B | |
| SCHEMBL10446532 | 0.74 | HTR2C (0.40) | NR3C2MAPK14ADRA2A | |
| SCHEMBL10447051 | 0.73 | SLC6A2 (0.39) | NR3C2MAPK14ADRA2ASLC6A2SLC6A4 | |
| SCHEMBL11272147 | 0.72 | MAOB (0.43) | MAPK14ADRA2ASLC6A2SLC6A4HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269755-B1 | DIBENZ b,e]OXEPIN DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME AS ACTIVE INGREDIENT | DAINIPPON PHARMACEUTICAL CO (JP) | 1993-11-18 | — | — | EP | disclosed |
| US-4889858-A | ANTIHYPOXIC AGENTS, ANTICONVULSANTS, LIPID PEROXIDATION INHIBITORS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-12-26 | — | — | US | disclosed |
| EP-0269755-A1 | DIBENZ b,e OXEPIN DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME AS ACTIVE INGREDIENT | Dainippon Pharmaceutical Co., Ltd. (JP) | 1988-06-08 | — | — | EP | disclosed |