SCHEMBL9738324

SCHEMBL9738324

COC(=O)c1ccc(NN2C(=O)C(C)=C(C)C2=O)cc1S(N)(=O)=O

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.49
CA1 P00915 7/20 0.49
CA9 Q16790 7/20 0.49
CA5A P35218 1/20 0.49
GAA P10253 2/20 0.40
CDK1 P06493 1/20 0.39
CA12 O43570 5/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
F10 P00742 1/20 0.38
MYC P01106 1/20 0.36
CA7 P43166 1/20 0.36
PDK2 Q15119 1/20 0.36
PDK4 Q16654 1/20 0.36
CA14 Q9ULX7 1/20 0.36
LMNA P02545 1/20 0.36
XPO1 O14980 1/20 0.36
YAP1 P46937 1/20 0.36
CA4 P22748 1/20 0.36
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9530201 0.89 CA1 (0.44) CA2CA1CA9CA5ACA12
SCHEMBL9530660 0.87 ALDH1A1 (0.40) CA2CA1CA9CA5AGAA
SCHEMBL9193525 0.80 CA2 (0.51) CA2CA1CA9CA5AGAA
SCHEMBL8539148 0.78 CA2 (0.59) CA2CA1CA9CA5AGAA
SCHEMBL22010624 0.75 CA2 (0.63) CA2CA1CA9CA5AGAA
SCHEMBL8539913 0.75 CA2 (0.55) CA2CA1CA9CA5AGAA
SCHEMBL21962894 0.74 CA2 (0.61) CA2CA1CA9CA5AGAA
SCHEMBL27453911 0.74 CA2 (0.54) CA2CA1CA9CA5AGAA
SCHEMBL27452999 0.74 CA2 (0.54) CA2CA1CA9CA5AGAA
SCHEMBL8030650 0.73 GAA (0.67) CA2CA1CA9CA5AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5129942-A For controlling monocotyledonous and dicotyledonous weeds on agricultural land KUREHA KAGAKU KOGYO K.K. (JP) 1992-07-14 US disclosed
US-5028255-A N-substituted-3-[(2,3-dimethylmaleimido)amino)]-benzenesulfonamide derivatives, hebicidal compositions and method of use KUREHA KAGAKU KOGYO K.K. (JP) 1991-07-02 US disclosed