Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | AGXT | P21549 | 2/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.32 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22048748 | 0.70 | ALPL (0.40) | MPOP2RX7NTRK1PTGS1PTGS2 | |
| SCHEMBL3298107 | 0.69 | IDO1 (0.58) | MPOIDO1AGXTPTGS1PTGS2 | |
| SCHEMBL9531057 | 0.68 | ALPL (0.40) | IDO1AXLKEAP1KDM4ESMN1; SMN2 | |
| SCHEMBL16016318 | 0.67 | MPO (0.41) | MPOP2RX7IDO1AGXTNTRK1 | |
| SCHEMBL13462054 | 0.64 | IDO1 (0.48) | IDO1AGXTKDM4ESMN1; SMN2DAO | |
| SCHEMBL16016327 | 0.64 | HRH4 (0.38) | MPOP2RX7IDO1AGXTPTGS1 | |
| SCHEMBL16020933 | 0.64 | SMN1; SMN2 (0.50) | MPOIDO1AGXTPTGS1PTGS2 | |
| SCHEMBL9532792 | 0.63 | PSEN1 (0.43) | MPOP2RX7NTRK1PTGS1PTGS2 | |
| SCHEMBL19225191 | 0.63 | MPO (0.40) | MPOP2RX7IDO1AGXTPTGS1 | |
| SCHEMBL16016323 | 0.63 | PTGS2 (0.42) | MPOP2RX7IDO1AGXTNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542872-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |