Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
| ▸ | CCKBR | P32239 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26764167 | 0.82 | ALDH1A1 (0.39) | POLB | |
| SCHEMBL9530208 | 0.81 | TSHR (0.33) | POLB | |
| SCHEMBL9530731 | 0.81 | TSHR (0.33) | POLB | |
| SCHEMBL23641866 | 0.75 | GAA (0.40) | — | |
| SCHEMBL9532098 | 0.73 | PLA2G10 (0.40) | PLA2G10PLA2G5POLBCCKBR | |
| SCHEMBL14086669 | 0.72 | PLA2G10 (0.43) | PLA2G10PLA2G5POLBCCKBR | |
| SCHEMBL3593084 | 0.70 | ALDH1A1 (0.55) | POLB | |
| SCHEMBL9636719 | 0.70 | ALDH1A1 (0.55) | POLB | |
| SCHEMBL5592121 | 0.70 | PLA2G10 (0.39) | PLA2G10PLA2G5POLBCCKBR | |
| SCHEMBL3562356 | 0.70 | POLB (0.37) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252744-B1 | 3-Beta-(3,4-disubstituted succinimido)azetidinones | LILLY CO ELI (US) | 1993-12-15 | — | — | EP | disclosed |
| US-4734498-A | 3β-succinimidoazetidinones as chiral intermediates | ELI LILLY AND COMPANY (US) | 1988-03-29 | — | — | US | disclosed |
| EP-0252744-A2 | 3-Beta-(3,4-disubstituted succinimido)azetidinones | ELI LILLY AND COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |