Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11799366 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HPGDHSD17B10RARBCYSLTR2 | |
| SCHEMBL9706457 | 0.79 | FFAR1 (0.44) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12473375 | 0.78 | S1PR2 (0.64) | ALDH1A1S1PR2S1PR1RARBCYSLTR2 | |
| SCHEMBL12405351 | 0.73 | S1PR2 (0.58) | ALDH1A1S1PR2S1PR1RARBCYSLTR2 | |
| SCHEMBL2860407 | 0.72 | S1PR2 (0.60) | ALDH1A1HPGDHSD17B10S1PR2S1PR1 | |
| SCHEMBL11795834 | 0.71 | PTGS2 (0.40) | S1PR1NPC1RAB9A | |
| SCHEMBL15614012 | 0.69 | ALDH1A1 (0.53) | ALDH1A1HPGDHSD17B10S1PR2S1PR1 | |
| SCHEMBL18076241 | 0.68 | ALDH1A1 (0.56) | ALDH1A1HPGDHSD17B10RARBCYSLTR2 | |
| SCHEMBL16915553 | 0.68 | KCNH2 (0.49) | ALDH1A1HSD17B10S1PR2S1PR1RARB | |
| SCHEMBL901587 | 0.68 | CYSLTR2 (0.48) | ALDH1A1HSD17B10S1PR2S1PR1RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561961-A1 | NOVEL HETEROCYCLIC AMIDINES AND GUANIDINES AS PLANT FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-29 | — | — | EP | disclosed |